New therapeutic approach in cancer research
The University Hospital Essen has developed a promising new approach to treating pancreatic cancer. This aggressive type of cancer, also known as ductal pancreatic adenocarcinoma (PDAC), is among the deadliest cancers worldwide. Despite decades of intensive research, the survival rate has barely improved – only about 10% of those affected survive the first five years after diagnosis.
A team of scientists from the Faculty of Medicine at the University of Duisburg-Essen, led by Prof. Dr. Katharina Lückerath and Dr. Marija-Trajkovic Arsic, is working on an innovative theranostic approach. This approach combines therapy and diagnosis to specifically target tumor cells while simultaneously modifying the tumor microenvironment to support the treatment. The unique aspect of this approach is its focus on the tumor's surrounding and supporting tissue, which comprises up to 90% of the tumor and plays a crucial role in its resistance to conventional therapies. By specifically modifying this tissue, the researchers hope to significantly improve treatment efficacy.
The German Research Foundation (DFG) is supporting this promising project with approximately €550,000. The research is currently in the preclinical stage, but the scientists are optimistic that their approach could represent a significant breakthrough in the treatment of pancreatic cancer in the future.
This innovative therapeutic approach could not only increase the survival chances of those affected, but also open up new avenues in cancer research and treatment. The progress made in Essen is yet another example of the cutting-edge research being conducted in North Rhine-Westphalia and underscores the importance of interdisciplinary collaboration in modern medicine.
Source: www.medizin.nrw
